![]() ![]() The aforementioned reasons have led to the use MALDI for the classification of large sets of samples from different sources and/or characteristics. Large sets of samples are analysed quickly in one single batch. Mass spectrometry using matrix assisted laser desorption ionization coupled to time of flight analysers, MALDI-TOF-MS, referred to herein as MALDI, has become popular during the last decade due to its high speed and sensitivity for detecting proteins and peptides. Mass-Up is distributed under license GPLv3 and it is open and free to all users at. Mass-Up brings knowledge discovery within reach of MALDI-TOF-MS researchers. Mass-Up software allows data preprocessing, as well as subsequent analysis including ( i) biomarker discovery, ( ii) clustering, ( iii) biclustering, ( iv) three-dimensional PCA visualization and ( v) classification of large sets of spectra data. Mass-Up, an open software multiplatform application for MALDI-TOF-MS knowledge discovery is herein presented. ![]() Although there are many software libraries and tools that can be combined for these kind of analysis, there is still a need for all-in-one solutions with graphical user-friendly interfaces and avoiding the need of programming skills. MALDI-TOF-MS can be also used in combination with Machine Learning techniques and statistical methods for knowledge discovery. MALDI-TOF mass spectrometry has become popular during the last decade due to its high speed and sensitivity for detecting proteins and peptides. ![]() Mass spectrometry is one of the most important techniques in the field of proteomics. ![]()
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